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The BPS Bioscience ARE Luciferase Reporter HepG2 Cell Line (Nrf2 Antioxidant Pathway) is specifically engineered to enable precise monitoring of the Nrf2 antioxidant response pathway. This stable, adherent HepG2 cell line incorporates a firefly luciferase reporter gene under the control of an Antioxidant Response Element (ARE), facilitating the direct correlation between luciferase expression and Nrf2 activation. Its reliable performance has been validated through stimulation with various compounds known to influence the antioxidant pathway.